Bioactive Natural Products: Chemistry And Biology -
: Includes nonribosomal peptides and sugar-decorated molecules that often function as potent antibiotics or toxins. 2. Biosynthesis and Biological Mechanisms
Natural products are categorized into major classes based on their chemical structures and biosynthetic origins: Bioactive Natural Products: Chemistry and Biology
Bioactive natural products represent a diverse array of chemical scaffolds evolved over millions of years to perform specific biological functions. These compounds, primarily secondary metabolites, serve as a cornerstone for modern drug discovery, contributing to approximately 24% of all approved drugs. 1. Classification and Chemical Diversity These compounds, primarily secondary metabolites, serve as a
: Polyphenolic compounds like curcumin and quercetin, known for their significant antioxidant, anti-inflammatory, and cardioprotective properties. The chemistry of these products is inextricably linked
The chemistry of these products is inextricably linked to their biology through specialized enzymatic pathways.
: Nitrogen-containing heterocyclic compounds often derived from amino acids. They frequently exhibit potent pharmacological effects, such as the analgesic properties of morphine.