It is listed as a Schedule 4 (Prescription Only) medicine in the Poisons Standard. This means it is illegal to possess or use without a valid prescription from an Australian doctor.

In Australia, (often called the "Barbie drug") is illegal to buy, sell, or advertise for tanning purposes .

The Therapeutic Goods Administration (TGA) has not approved Melanotan 2 for any use in Australia due to significant safety concerns.

The TGA and medical experts strongly advise against its use due to several reported risks: Don't risk using tanning products containing melanotan