Add a glowing red "laser eye" or "eye flare" effect to the subject of the video.

Use speedline overlays or comic book filters to give the frame an authentic anime feel.

You can find various versions on platforms like YouTube or Voicemod's Tuna . The most popular version is the "Omae Wa Mou Shindeiru" (You are already dead) buildup followed by the high-pitched "NANI?!". Visual Elements:

Apply a "Chaos" or "Shake" filter simultaneously with the sound effect to simulate a high-energy explosion of shock.

Watch this tutorial to see how to layer filters and sound for a professional-looking 'Nani' effect:

Editing a "Nani?!" moment usually involves a combination of audio and visual cues to maximize the comedic impact:

Place the sound effect exactly at the moment of realization or impact. For a classic meme feel, freeze the frame on a "snapshot" of the subject's face just as the audio peaks.